2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-118412
    Terallethrin
    		Inhibitor
    Terallethrin (M108) is a synthetic pyrethroid widely used as an insecticide in agricultural and household Settings.
    Terallethrin
  • HY-N2876
    Anisofolin A
    		Inhibitor
    Anisofolin A is a flavonoid that can be isolated from Anisomeles indica. Anisofolin A has antimalarial activity (IC50: 4.39 μM), and antimycobacterium activity (IC50: 4.50 μM) against M. tuberculosis H37Ra.
    Anisofolin A
  • HY-N12700
    Puberulic acid Ⅰ
    		Inhibitor
    Puberulic acid Ⅰ possesses anti-malarial activity with an IC50 value of 0.050 µM against Plasmodium falciparum K1 (chloroquine-resistant).
    Puberulic acid Ⅰ
  • HY-B0529R
    Azlocillin (Standard)
    		Inhibitor
    Azlocillin (Standard) is the analytical standard of Azlocillin. This product is intended for research and analytical applications. Azlocillin, an antibiotic, is a semisynthetic penicillin, and has broad-spectrum antibacterial activity. Azlocillin is active against drug-tolerant B. burgdorferi sensu stricto JLB31 infection.
    Azlocillin (Standard)
  • HY-W015818R
    2-Benzoxazolinone (Standard)
    		Inhibitor
    2-Benzoxazolinone (Standard) is the analytical standard of 2-Benzoxazolinone. This product is intended for research and analytical applications. 2-Benzoxazolinone is an anti-leishmanial agent with an LC50 of 40 μg/mL against L. donovani. A building block in chemical synthesis. 1,3-Benzoxazol-2(3H)-one derivatives have antimicrobial activity against a selection of Gram-positive, Gram-negative bacteria and yeasts. Derivatives as anti-quorum sensing agent[4].
    2-Benzoxazolinone (Standard)
  • HY-A0106R
    Levamisole (Standard)
    		Inhibitor
    Levamisole (Standard) is the analytical standard of Levamisole. This product is intended for research and analytical applications. Levamisole ((-)-Levamisole), an anthelmintic agent with immunomodulatory properties. Levamisole acts as a positive allosteric modulator (PAM) for the α3β2 (EC50=300 μM) and α3β4 (EC50=100 μM) subtype of nAChRs. Orally active.
    Levamisole (Standard)
  • HY-B2029R
    Phosalone (Standard)
    		Inhibitor
    Phosalone (Standard) is the analytical standard of Phosalone. This product is intended for research and analytical applications.
    Phosalone (Standard)
  • HY-171190
    ELQ-316
    		Inhibitor
    ELQ-316 is an endochinlike quinolone compound and an anti-parasite agent. ELQ-316 demonstrates a great efficacy against acute and chronic experimental toxoplasmosis.
    ELQ-316
  • HY-169790
    Phomarin
    		Inhibitor
    Phomarin is an inhibitor for dihydrofolate reductase (DHFR), and exhibits potential antimalarial activity.
    Phomarin
  • HY-126392
    Isonardoperoxide
    		Inhibitor
    Isonardoperoxide is a potent antimalaria agent with an EC50 of 0.6 μM for Plasnwdium fulciparum malaria.
    Isonardoperoxide
  • HY-137034
    (+)-Secolongifolene-diol
    (+)-Secolongifolene-diol is a sesquiterpene, that can be isolated from the marine fungal Drechslera sp. (+)-Secolongifolene-diol exhibits slightly weak effectiveness in antioxidation, antimicrobial and antifouling aspects.
    (+)-Secolongifolene-diol
  • HY-130752
    VNI
    		Inhibitor
    VNI is an effective inhibitor of CYP51. VNI can inhibit sterol synthesis in Trypanosoma cruzi, exhibiting anti-Trypanosoma cruzi activity.
    VNI
  • HY-B1344R
    Oxantel (pamoate) (Standard)
    		Inhibitor
    Oxantel (pamoate) (Standard) is the analytical standard of Oxantel (pamoate). This product is intended for research and analytical applications. Oxantel pamoate is a widely available dewormer, potently against Trichuris muris and Hookworms.
    Oxantel (pamoate) (Standard)
  • HY-169339
    Villalstonine
    		Inhibitor
    Villalstonine is a bisindole alkaloid with various biological activities including anticancer, antimalarial, and antiamoebic activities. Villalstonine exhibits potent antiplasmodial activity against the multidrug-resistant K1 strain of P. falciparum with an IC50 value of 0.27 μM.
    Villalstonine
  • HY-N1584AR
    Halofuginone (hydrobromide) (Standard)
    		Inhibitor
    Halofuginone (hydrobromide) (Standard) is the analytical standard of Halofuginone (hydrobromide). This product is intended for research and analytical applications. Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects.
    Halofuginone (hydrobromide) (Standard)
  • HY-134220
    Doramectin monosaccharide
    Doramectin monosaccharide is an acid degradation product of Doramectin (HY-17035), a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. Doramectin undergoes acid-catalyzed hydrolysis to form doramectin monosaccharide.
    Doramectin monosaccharide
  • HY-13735AR
    Quinacrine (dihydrochloride) (Standard)
    		Inhibitor
    Quinacrine (dihydrochloride) (Standard) is the analytical standard of Quinacrine (dihydrochloride). This product is intended for research and analytical applications. Quinacrine (Mepacrine) dihydrochloride is an orally bioavailable antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine dihydrochloride suppresses NF-κB and activate p53 signaling, which results in the induction of the apoptosis.
    Quinacrine (dihydrochloride) (Standard)
  • HY-W774926
    Permethrin-d6
    		Inhibitor
    Permethrin-d6 (NRDC-143-d6) is deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide and a high selectively inhibitor of the Mitochondrial complex I, found in sediment and water samples. Permethrin shows estrogenic in vivo and anti-estrogenic activity in vitro. Permethrin also acts as a neurotoxin affecting neuron membranes by prolonging Sodium channel activation. Permethrin decreases resistance to bacterial infections in medaka (Oryzias latipes).
    Permethrin-d<sub>6</sub>
  • HY-N7236
    Pervicoside B
    		Inhibitor
    Pervicoside B is a glycoside C isolated from Neothyone gibbosa sea cucumber. In vitro studies have shown that Pervicoside B has a potent antiparasitic effect against Leishmania mexicana, inhibiting 100% of promastigotes at 5-10 μg/mL. Pervicoside B also exhibits strong antifungal activity against Aspergillus niger, with MIC values ranging from 4.65 to 16.7 μg/mL. Pervicoside B has potential applications in the inhibition of parasitic infections and fungal diseases.
    Pervicoside B
  • HY-135625
    BPH-1218
    BPH-1218 is an inhibitor of squalene synthase (SQS), with the IC50 of 31 nM and 64 nM for TcSQS and HsSQS, respectively, that can be used as an anti-infective agent.
    BPH-1218
Parasite Isoform Comparison

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